Commentary: The Brain Basis for Misophonia

Response: Commentary: The Brain Basis for Misophonia

The Brain Basis for Misophonia

Misophonia is an affective sound-processing disorder characterized by the experience of strong negative emotions (anger and anxiety) in response to everyday sounds, such as those generated by other people eating, drinking, chewing, and breathing [1-8]. The commonplace nature of these sounds (often referred to as "trigger sounds") makes misophonia a devastating disorder for sufferers and their f...

Commentary: New View on Treatment of Drug Dependence

In the 1960s, discovery of pleasure system (defined as reward system) in the brain that may underlie drug reward and addiction encouraged many scientists to investigate the mechanisms by which drug abuse affects central nervous system function. In this regard, investigators developed several drugs targeting the brain reward system for drug dependence therapy. However, no positive results obtain...

Proposed Diagnostic Criteria for Misophonia: A Multisensory Conditioned Aversive Reflex Disorder

Misophonia is an underinvestigated condition often typified as an extreme sensitivity to specific, low volume sounds and images that elicit an intense physiological and emotional response (Jastreboff and Jastreboff, 2002, 2014; Edelstein et al., 2013; Schröder et al., 2013; Wu et al., 2014; Cavanna and Seri, 2015; Dozier, 2015a, 2017). While misophonia has been described as a distinct psychiatr...

Treatments for Decreased Sound Tolerance (Hyperacusis and Misophonia)

Decreased sound tolerance (DST) is an underappreciated condition that affects the lives of a significant portion of the general population. There is lack of agreement regarding definitions, specific components, prevalence, methods of evaluation, and methods of treatment. Limited data are available on the results of treatments. Research is scant and constrained by the lack of an animal model. Th...